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Sorafenib is used in the treatment of various diseases such as liver cancer and kidney cancer. In the case of using Basrat oral solution, the relative gain is 38-49%. Sorafenib produces peak plasma concentrations in about 3 hours and reduces bioavailability by 29% after high-fat foods.

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Sorafenib is a kinase inhibitor that reduces the proliferation of cancer cells. Also, sorafenib prevents the growth and angiogenesis of liver, kidney, and thyroid cancer (DTC) tumors.

Sorafenib is a cancer drug that interferes with the growth and spread of cancer cells in the body. Sorafenib drug is used in the treatment of liver cancer, thyroid cancer, and types of kidney cancer called advanced renal cell carcinoma.

Therapeutic Fields​

Dosage Form

Tablet 200mg

Mechanism of action

This drug prevents the growth of new blood vessels towards the tumor by inhibiting several intracellular and cell surface kinases, thus reducing the proliferation of tumor cells.

Uses of Sorafenib

Inoperable hepatocellular carcinoma
Advanced renal cell carcinoma
Locally differentiated and metastatic thyroid carcinoma, or recurrent and resistant to radioactive iodine treatment

Method of Use

The dosage of each drug is determined by the doctor, but the usual dosage of this drug is 800 mg per day.
In case of side effects, depending on the doctor’s opinion, it may be necessary to reduce the dosage of the drug.

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