Saffron, magnesium & B6 – PMS Supplement

Saffron, Magnesium & B6 is a natural remedy featuring saffron (Crocus Sativus L.,) extract with high-potency, magnesium and vitamin B6. Saffron is effective in treating mild to moderate depression via a serotonergic mechanism. Also, it can be used to stimulate menstruation or ease the blood flow, work against spasms and relieve pain and irritability, all of which are common during periods. Magnesium and B6 reduce fatigue, support normal muscle function and psychological conditions.

Saffron, Mg and vitamin B6 have been linked to mental health and quality of life (QoL)  Since the symptoms of depression and PMS overlap, this combination can significantly reduce the severity of PMS symptoms.

Therapeutic Fields​

Antidepressant

Relive PMS symptoms

Improve mood

Saffron

Saffron has traditionally been used to treat a variety of diseases, such as primary dysmenorrhea and premenstrual tension. Based on clinical studies, receiving 15mg capsules of saffron twice a day for two menstrual cycles could relieve and significantly improves PMS symptoms and PMD.

• Alleviating Symptoms of PMS
• Depression by elevating serotonin level
• Aphrodisiac properties
• supports weight loss

The effect of saffron on the severity of PMS

This randomized triple-blind controlled clinical trial was carried out with 78 students aged 18-35 years and for a period of two menstrual cycles. the two groups had significant differences in terms of changes in the mean severity of PMS over time.

Vitamin B6

Vitamin B6 known as Pyridoxine, is a water-soluble vitamin that is required for over 100 enzyme reactions in the body. One of its main roles is in helping the body metabolize proteins, fats, and carbohydrates for energy. B6 is also involved in:

• Alleviating Symptoms of PMS
• Reduce Estrogen Dominance
• Production of Progesterone
• creating neurotransmitters, including GABA serotonin and dopamine

Selenium

Magnesium is one of the most essential minerals to help balance hormones, and involves as a cofactor in more than 300 enzymatic systems. sufficient magnesium supports:

• Alleviating Symptoms of PMS
• Estrogen balance by affecting phase 2 metabolism of estrogen
• Production of sex hormones
• Healthy Serotonin Levels by helping conversion of tryptophan into serotonin
• Sleep by increasing production of melatonin
• Lower blood sugar by increasing insulin sensitivity

Dosing and Adminstration

One or two capsules daily, with the main meal and a full glass of water

Warnings/Precautions

Use with caution in bipolar disorders, Renal impairment,lnflammatory bowel disease, Heart failure, Decompensated cirrhosis, Baseline electrolyte abnormalities.

Use with extreme caution in Neuromuscular disease and Intestinal obstruction disorder. surgery: stop taking saffron at least two weeks before a scheduled sugery

Contraindications

Risk X: Sodium/Calcium polystyrene sulfonate.

Side Effects

Saffron, Mg and B6 is likely safe in recommended amounts; Allergic reaction, nausea, vomiting, headache and abdominal pain can occur in some people.