Morphine Sulfate

Morphine sulfate is a powerful opioid pain medication derived from the opium poppy plant. Moreover, It is available in various forms, including tablets, capsules, injections, suppositories, and oral solutions. Also, it is a Schedule II controlled substance in the United States due to its high potential for abuse and dependence.

Technical Data

Chemical formula: C17H19NO3•H2SO4•5H2O

Molecular weight: 758.83 g/mol

CAS number: 6211-15-0

PubChem CID: 5280846

Melting point: 250°C (decomposes)

Solubility: 1 in 21 parts water, 1 in 790 parts alcohol, 1 in 1,100 parts chloroform

pKa: 8.03

Appearance: White, crystalline powder

Pharmacology: Morphine is a full opioid agonist, meaning it binds to and activates opioid receptors in the central nervous system (CNS). Moreover, This activation produces a variety of effects, including:

• Pain relief
• Sedation
• Relaxation
• Euphoria
• Respiratory depression

Dosage: The dosage varies depending on the individual’s age, weight, medical condition, and severity of pain. So, it is typically started at a low dose and gradually increased as needed.

Side effects: Common side effects of morphine include:

• Constipation
• Nausea and vomiting
• Drowsiness
• Dizziness
• Itching
• Urinary retention

Serious side effects: More serious side effects of it can include:

• Respiratory depression
• Slowed heart rate
• Seizures
• Coma

Contraindications: Morphine sulfate is contraindicated in people with:

• Hypersensitivity to morphine or other opioids
• Severe respiratory depression
• Paralytic ileus
• Acute bronchial asthma

Drug interactions: It can interact with many other medications, including:

• Alcohol
• Benzodiazepines
• Antidepressants
• Anticonvulsants
• Muscle relaxants

Warnings and precautions:

• Morphine can be addictive and should be used only as directed by a healthcare professional.
• Also, It can cause respiratory depression, which can be fatal. It is important to use morphine sulfate in a monitored setting, especially if you have breathing problems.
• In addition, This medicine API can cause drowsiness and impair your ability to drive or operate machinery.
• It can interact with many other medications. Also, it is important to tell your healthcare professional about all the medications you are taking, including over-the-counter medications and herbal supplements.

Image of Morphine Sulfate chemical structure:

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