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Buprenorphine Hydrochloride

Chemical formula: C29H42ClNO4

Molecular weight: 504.10 g/mol

CAS number: 53152-21-9

Appearance: White to off-white crystalline powder

Melting point: 278-280 °C


  • Water: Slightly soluble (1:2000)
  • Ethanol: Freely soluble (1:5)
  • Chloroform: Freely soluble (1:5)

pKa: 8.7

Log P: 4.11

pH: 4.5-6.5

Storage: Store at room temperature (15-25°C) in a tightly closed container protected from light.

Stability: Stable for 24 months when stored as recommended.

Stock Code : 08f762b41207 Category :

Uses of Buprenorphine:

  • Buprenorphine HCl is a semi-synthetic opioid agonist-antagonist used to treat opioid use disorder (OUD) and chronic pain. It is available in various forms, including sublingual tablets, buccal films, and transdermal patches.

Mechanism of action:

  • Buprenorphine Hydrochloride binds to the mu-opioid receptors in the brain, producing partial agonist effects. This means it can produce some of the same effects as other opioids, such as pain relief and euphoria, but to a lesser extent.
  • It also has antagonist effects at the kappa-opioid receptors. This means it can block the effects of other opioids, making it difficult to get high from them.

Side effects:

  • The most common side effects of Buprenorphine Hydrochloride include constipation, nausea, vomiting, drowsiness, and headache.
  • More serious side effects can occur, such as respiratory depression, allergic reactions, and adrenal insufficiency.


  • PluviaEndo‘s Buprenorphine Hydrochloride should not be used by people who are allergic to it or who have severe respiratory depression.
  • It should also be used with caution in people with liver or kidney problems, pregnant or breastfeeding women, and people who are taking other medications that can cause respiratory depression.


Disclaimer: I am not a medical professional and cannot provide medical advice. If you have any questions about Buprenorphine Hydrochloride, please talk to your doctor or pharmacist.

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